![Butel arc 500 1.1](https://kumkoniak.com/117.png)
![butel arc 500 1.1 butel arc 500 1.1](http://lampes-et-tubes.info/alxe/al013c.jpg)
B.1.627 and B.1.631 were mostly sampled in the USA, whereas B.1.634 was most commonly found in Mexico ( Figure 1B). All four lineages were predominantly sampled in North America (89.5% of sequences), either in the United States of America (USA) or Mexico.
![butel arc 500 1.1 butel arc 500 1.1](https://contents.mediadecathlon.com/p1822799/k$4fc0e01dd3e9e6426bd8b777b1c097f5/sq/FLECHES+CLUB+500+CB+X3+CARBONE+ARC+A+POULIES.jpg)
This event raises important questions regarding the role and potential effects of recombination on SARS-CoV-2 evolution. This scenario is supported by the spatiotemporal distribution of these lineages across the USA and Mexico during 2021, suggesting that the recombination event originated in this geographical region. By accounting for several deletions in NSP6, Orf3a, and S, we conclude that the B.1.628 major cluster, now designated as lineage XB, originated from a recombination event between viruses of B.1.631 and B.1.634 lineages. Our analyses reveal well-supported phylogenetic differences between the Orf1ab region encoding viral non-structural proteins and the rest of the genome, including Spike (S) protein and remaining reading frames. Here, we present a detailed phylogenetic analysis of four SARS-CoV-2 lineages to investigate the possibility of virus recombination among them. Although recombination is a feature of coronavirus evolution, previously detected recombinant lineages of SARS-CoV-2 have shown limited circulation thus far.
![Butel arc 500 1.1](https://kumkoniak.com/117.png)